The number of ORFs found = 1

ORF Gene Chromosome Start Coord Stop Coord Phenotype Spurious ORF Overlapping ORF Overlapping Spurious
YOR136W IDH2 XV 580249 581358 viable YOR135C yes
CYGD description: isocitrate dehydrogenase (NAD+) subunit 2. mitochondrial
SGD description1: tricarboxylic acid cycle; description2: isocitrate dehydrogenase (NAD+)
YPD MitoP2 Saccharomyces Deletion Project

Growth Rates: Homozygous Diploid Pool
Time Course 1 Time Course 2 Homozygous Diploid: YOR136W
YPD0.972775 1.005746 click on image to enlarge
YPDGE0.900764 0.857172
YPG0.711702 0.657229
YPE0.778693 0.778024
YPL0.629742 0.571492
YPD.1DNP 1.002445
YPD.25DNP 0.984764
YPG.1DNP 0.693210
YPG.25DNP 0.639717
no. of probes4 4
tag measurements40 73
F-statistics55.691581 126.955632
-log(p-value)12.988074 33.940954
max. difference0.343032 0.434253

Growth Rates: Heterozygous Diploid Pool
Time Course 1 Time Course 2 Heterozygous Diploid: YOR136W
YPD0.951210 0.970493 click on image to enlarge
YPDGE0.951065
YPG0.971531 0.978687
YPE1.096041
YPL0.947627
YPD.1DNP 0.905293
YPD.25DNP 1.026826
YPG.1DNP 1.063806
YPG.25DNP 1.032520
no. of probes1 1
tag measurements11 12
F-statistics2.797047 2.816798
-log(p-value)0.839753 0.853467
max. difference0.148415 0.158512

Proteomics Peptide Identifications
yplDG1me yplDG2me yplDG3me ypl01me ypl02me ypl14me ypl15me ypl01meFT ypl02meFT
00 24 80 42 4
yplDG1ma ypl01ma ypl02ma ypl14ma ypl15ma ypl01maFT ypl02maFT
615 1719 1519 0
ypd4me ypd13me ypd4ma ypd13ma
42 1714
scl01me scl01meFT scl01ma scl01maFT
410 1416
scd01me scd01meFT scd01ma scd01maFT
70 1613

Mitochondrial Expression Data
YPD YPL SCD SCL YPL:YPD SCL:SCD
21113.7529487.61 29724.7513274.98 1.40-2.24
For ratio calculations, if value < 0, denotes negative inverse of ratio

Phenotypes
CYGD respiratory deficient phenotype catalog
CYGD carbohydrate utilization defect phenotype catalog

Metabolism
CYGD carbohydrate metabolism functional catalog
MitoP
Mitoprot analysis of yeast genome
predicted length of signal peptide: 27
probability of mitochondrial import: 0.9961

Homology
homology to bacterial protein similarity 32% identical to E. coli NAD(P)(+)-dependent isocitrate dehydrogenase
homology to R. prowazekii : CAA14727.1
R. prowazekii description: ISOCITRATE DEHYDROGENASE (icd)
log10 R. prowazekii E-value: -55.221849

Other Expression Studies
found increased: yes
Reference

Two-hybrid Database
Biomolecular Interaction Network Database
Medline link


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