The number of ORFs found = 1

ORF Gene Chromosome Start Coord Stop Coord Phenotype Spurious ORF Overlapping ORF Overlapping Spurious
YKL085W MDH1 XI 278765 279769 viable
CYGD description: malate dehydrogenase precursor, mitochondrial
SGD description1: tricarboxylic acid cycle; description2: malic enzyme
YPD MitoP2 Saccharomyces Deletion Project

Growth Rates: Homozygous Diploid Pool
Time Course 1 Time Course 2 Homozygous Diploid: YKL085W
YPD1.008785 1.007078 click on image to enlarge
YPDGE1.006327 1.001002
YPG0.860912 0.800148
YPE0.996918 0.939727
YPL0.898865 0.813444
YPD.1DNP 0.996347
YPD.25DNP 0.989985
YPG.1DNP 0.863229
YPG.25DNP 0.912124
no. of probes4 4
tag measurements44 76
F-statistics10.892290 76.279883
-log(p-value)5.116162 28.735373
max. difference0.147873 0.206930

Growth Rates: Heterozygous Diploid Pool
Time Course 1 Time Course 2 Heterozygous Diploid: YKL085W
YPD1.024120 1.033502 click on image to enlarge
YPDGE1.005248
YPG0.995638 1.018991
YPE1.001633
YPL1.019694
YPD.1DNP 1.005196
YPD.25DNP 1.022387
YPG.1DNP 1.004838
YPG.25DNP 1.005782
no. of probes4 4
tag measurements44 52
F-statistics0.432888 2.763986
-log(p-value)0.105743 1.520059
max. difference0.028482 0.028665

Proteomics Peptide Identifications
yplDG1me yplDG2me yplDG3me ypl01me ypl02me ypl14me ypl15me ypl01meFT ypl02meFT
13 70 38 40 0
yplDG1ma ypl01ma ypl02ma ypl14ma ypl15ma ypl01maFT ypl02maFT
1928 2427 2627 3
ypd4me ypd13me ypd4ma ypd13ma
11 2431
scl01me scl01meFT scl01ma scl01maFT
414 3427
scd01me scd01meFT scd01ma scd01maFT
112 3123

Mitochondrial Expression Data
YPD YPL SCD SCL YPL:YPD SCL:SCD
10204.6930949.89 15509.9421240.96 3.031.37
For ratio calculations, if value < 0, denotes negative inverse of ratio

Phenotypes
CYGD respiratory deficient phenotype catalog
CYGD carbohydrate utilization defect phenotype catalog

Metabolism
CYGD carbohydrate metabolism functional catalog
MitoP
Mitoprot analysis of yeast genome
predicted length of signal peptide: 18
probability of mitochondrial import: 0.9870

Homology
homology to R. prowazekii : CAA14835.1
R. prowazekii description: MALATE DEHYDROGENASE (mdh)
log10 R. prowazekii E-value: -21.154902

Other Expression Studies
found increased: yes
Reference

Two-hybrid Database
Biomolecular Interaction Network Database
Medline link


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