this project strains from the were monitored under 9 different media conditions
using molecular barcodes. This database contains both the raw data and
growth rates calculated for each strain in each media condition. Strains
can be searched by ORF name or gene name to access plots and growth
measures for each strain. The database is hyperlinked with public databases
of other yeast resources (SGD,
heterozygous diploid and 4706 homozygous diploid deletion strains were
monitored in parallel on fermentable (YPD, YPDGE) and non-fermentable
substrates (YPG, YPE, YPL). The project aims to increase the understanding
of mitochondrial function and biogenesis in the context of the cell.
Information on the links:
Analysis, the homozygous diploid strains were grouped into three
classes: class I lists genes without significant growth differences
between conditions; class II has genes with a fermentable growth defect;
class III genes with a non-fermentable growth deficiency. Each list
is interlinked with the database. In an additional analysis class IIIa
and class IIIb were combined (different degrees of non-fermentable growth
defects) and narrowed to 466 genes by removing spurious ORFs. The 466
genes were divided into 201 previously known mitochondrial genes (localization
or function); 161 with unknown localization; 104 localized outside mitochondria.
Homology yeast genes are listed that are similar to proteins
in Rickettsia prowazeckii and bacteria in general.
Prediction yeast genes are listed according to whether they are
known mitochondria-related proteins (MitoP) or have a high probability
of containing a mitochondrial import sequence (Mitoprot).
External data are functional and phenotypic classifications acquired
from public databases, mostly from CYGD.
data are available for download from homozygous and heterozygous
pools (two repeat experiments).
database serves to support:
Steinmetz, Curt Scharfe, Adam M. Deutschbauer, Dejana Mokranjac, Zelek
S. Herman, Ted Jones, Angela Chu, Guri Giaever, Holger Prokisch, Peter
J. Oefner & Ronald Davis. . Submitted.
Web site © 2002 Stanford Genome
In addition to original data, this
web site and its associated links contain information gleened from public
data. While the public data has been faithfully downloaded into the
YDPM database, no representations are made regarding the accuracy of
the public data.